4 Ways Magnesium Promotes Brain Health

Many symptoms related to psychological disorders are linked to a magnesium deficiency.

Magnesium is an essential cofactor in more than 300 enzymatic reactions in the brain, the heart and the bones. Magnesium is an important component in every cell in the body.

Unfortunately, a deficiency in this mineral is one of the most common nutritional deficiencies seen today.

Magnesium, the mind mineral, could be the missing link in mental health.

What is Magnesium?

Magnesium is considered a macromineral. This means that you need to consume magnesium in larger amounts in your diet.

Macrominerals, like magnesium, are those minerals that are required in quantities greater than 100 mg per day.

Magnesium is found in many plant and animal foods as well as supplements. As a general rule of thumb, foods that are rich in fiber tend to also be rich in magnesium.

Unfortunately, our soil is depleted and the magnesium content of food is not what it was 50 years ago.

Conventional doctors these days fail to check blood magnesium levels, let alone intracellular levels. You deserve better testing for your health.

Assessing magnesium status can be difficult in conventional lab tests, as most of it resides in cells and bones. Assessing magnesium levels only in the blood tell us little about total body magnesium concentrations or the amounts stored in tissues.

This is why we do the most advanced micronutrient testing in the world. We analyze the nutrients in the blood AND how much of those nutrients get into the cells (where they belong).

What is the Role of Magnesium in Brain Health?

  • Magnesium is needed to create neurotransmitters

    Magnesium is needed to regulate and balance key mood-regulating neurotransmitters like GABA (inhibitory neurotransmitter) and Glutamate (excitatory neurotransmitter), both of which are involved in mental health disorders. Magnesium is also needed for dopamine and serotonin production and regulation.

  • Magnesium helps with depression and anxiety

    Research has shown there’s a link between very low magnesium intakes and the development of depression, especially in younger adults1. A novel study found that supplementation with magnesium results in improved depression and to some extent anxiety scores in moderately depressed adults2,3. Magnesium also reduces neuroinflammation, which further prevents depression and anxiety.

  • Magnesium helps with Attention Deficit Hyperactivity Disorder (ADHD)

    Similar to other mental health disorders, rates of ADHD are on the rise. Research has shown that children with ADHD have significantly low levels of magnesium and are likely to be “magnesium deficient”4.  Supplementation has been shown to improve ADHD symptoms in patients.

  • Magnesium increases brain plasticity
  • Brain plasticity is a term for how brain cells communicate. It is the brain’s ability to form new communication pathways, or synapses, between brain cells. This allows us to learn and form or retain new memories.  As we age, brain plasticity decreases and cognitive functions decline. Increased levels of brain plasticity are protective of the brain and prevent neurodegenerative diseases like Alzheimer’s disease. Magnesium has been shown to be a critical factor in increasing brain plasticity5, which holds promise for preventing cognitive loss.

Should I Take a Magnesium Supplement?

The answer is likely yes.

The general population is deficient in magnesium and other nutrients for several reasons.

Magnesium plays important roles in mental health and should be considered a go-to brain supplement.

Try the brain-healthy form called magnesium L-threonate. Our product, called Magne 5, has 144 mg magnesium L- threonate per serving.

This L-threonate form can cross the blood brain barrier and directly increase concentrations of magnesium within the brain.

Restoring levels of this mighty mineral is essential to emotional and behavioral well-being.

Summary of Information:

  • Magnesium is an essential mineral needed for mental health.
  • Higher intakes of magnesium have been shown to be protective of the brain. Magnesium is needed to create key neurotransmitters and to increase communication pathways for brain cells. It also prevents depression and anxiety and can help with ADHD treatment.
  • Check out our brain health supplement called Magne 5. It is loaded with 144 mg magnesium L-threonate. This form of magnesium crosses into the brain to directly raise brain magnesium concentrations.



  1. Tarleton et al., 2015: https://www.ncbi.nlm.nih.gov/pubmed/25748766
  2. Tarelton et al., 2017: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487054/
  3. Boyle et al., 2017: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452159/
  4. Hermelin et al., 1997: https://www.ncbi.nlm.nih.gov/pubmed/9368236
  5. Li et al., 2014: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172865/

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